What Medication Can interfere with Oral Contraceptives?


All told, there are nearly 500 drugs known to interact with oral contraceptives, but only a small percentage involve a serious interaction.

There are 19 known drugs to have what is considered to be a major interaction with oral contraceptives, specifically, with ortho-novum 1/35.

These drugs are listed below, in both marketing name and drug name. All potential patients receiving oral contraceptives should inform their health care professional of every drug they are currently taking as well as any changes in any drugs they are taking.

It is also wise to check with one's pharmacist when filling a prescription since not all doctors have the information that one's pharmacist will have about drug interactions.

Acitretin-containing products
• Soriatanve
• Soriatane CK

Agenerase (amprenavir)

CellCept (mycophenolate mofetil)

Dantrolene-containing products
• Datrolene
• Dantrium
• Dantrium intravenous

Fosamprenavir-containing products
• Lexiva
• Telzir

Griseofulvin-containing products:
• Fulvicin P/G
• Fulvicin U/F
• Grufulvin V
• Grisactin 250
• Grisactin 500
• Grisactin Ultra
• Griseofulicin
• Griseofulvic

Incivek (telaprevir)

Isotretinoin-containing products
• Absorica
• Accutane
• Amnesteem
• Claravis
• Myorisan
• Sotret
• Zenatane

Myfortuc (mycophenolic acid)

Panhematin (hemin)
Pomalyst (pomalidomide)

Revlimid (lenalidomide)

Targretin (bexarotene)
Tegison (etretinate)
Thalomid (thalidomide)
Tracleer (bosentan)

Tranexamic acid-containing products
• Cyklokapron
• Lysteda

Victrelis (boceprevir)

Zanaflex (tizanidine)


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